bp_pairwise_kaks.pl man page on Pidora

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BP_PAIRWISE_KAKS(1)   User Contributed Perl Documentation  BP_PAIRWISE_KAKS(1)

NAME
       pairwise_kaks - script to calculate pairwise Ka,Ks for a set of
       sequences

SYNOPSIS
       pairwise_kaks.PLS -i t/data/worm_fam_2785.cdna [-f
       fasta/genbank/embl...] [-msa tcoffee/clustal] [-kaks yn00/codeml]

DESCRIPTION
	 This script will take as input a dataset of cDNA sequences verify
	that they contain no stop codons, align them in protein space,
	project the alignment back into cDNA and estimate the Ka
	(non-synonymous) and Ks (synonymous) substitutions based on the ML
	method of Yang with the PAML package.

	Requires:
	* bioperl-run package
	* PAML program codeml or yn00
	* Multiple sequence alignment programs Clustalw OR T-Coffee

	Often there are specific specific parameters you want to run when you
	a computing Ka/Ks ratios so consider this script a starting point and
	do not rely it on for every situation.

FEEDBACK
   Mailing Lists
       User feedback is an integral part of the evolution of this and other
       Bioperl modules. Send your comments and suggestions preferably to the
       Bioperl mailing list.  Your participation is much appreciated.

	 bioperl-l@bioperl.org			- General discussion
	 http://bioperl.org/wiki/Mailing_lists	- About the mailing lists

   Reporting Bugs
       Report bugs to the Bioperl bug tracking system to help us keep track of
       the bugs and their resolution. Bug reports can be submitted via the
       web:

	 http://bugzilla.open-bio.org/

AUTHOR
	Jason Stajich jason-at-bioperl-dot-org

perl v5.14.1			  2011-07-22		   BP_PAIRWISE_KAKS(1)
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